万田発酵

TOPAcademic data
Academic data


Manda Koso’s possibilities seen from a scientific point of view.

We identify the components contained in Manda Koso and analyze its effects to carry out scientific verification through an experiment involving test tubes and animals, as well as by taking advantage of statistics. Today, in many areas of anti-oxidation, anti-aging, immunity, and stress, Manda Koso’s academic data is published on a number of research papers and magazines.
In addition, Manda Koso has not obtained permission or notification as a food for specified health uses and a functional food.

Published academic themes and titles.

Anti-oxidation

[Title]

Free Radical Scavenging Action of MANDA(Japanese)


[Journal] The Clinical Report Vol.28 No.2, 1994

[Author] Kawai, et al.


[Target] test tube

[Title]

Effects of a fermented vegetable product on hemolysis and lipid preoxidation of Japanese flounder erythrocytes


[Journal] Fisheris Science 68, 2002

[Author] Ashida, et al.


[Target] flounder, erythrocytes

[Title]

The dietary effects of a fermented vegetable product on glutathioone peroxidase activity and lipid peroxidation of Japanese flounder Paralichthys olivaceus


[Journal] Fisheris Science 72, 2006

[Author] Ashida, et al.


[Target] flounder, serum, liver

Cancers

[Title]

Antitumor and Immunopotentiating Effects of Manda Enzyme


[Journal] Natural Product Sciences 2(1), 1996

[Author] Hwang, et al.


[Target] mouse, whole body

[Title]

Postoperative Effect of Manda on NK Cell Activity in Cancer Patients(Japanese)


[Journal] Biotherapy 13(7), 1999

[Author] Yamamoto, et al.


[Target] human, whole body

[Title]

Inhibitory Effects or Fermentive Foods Prepared from Plant Materials on Tumor Growth and Metastasis to Lung (Japanese)


[Journal] The Japanese Journal of Constitutional Medicine Vol.61 No.1/2, 1999

[Author] Kimura, et al.


[Target] mouse, whole body

[Title]

Inhibition of Human Breast Cancer Cell Growth and Enzymatic Activity by a Fermented Nutraceutical: An in Vitro and in Vivo Study


[Journal] Annuals of the New York Academy of Sciences 1155, 2009

[Author] Marotta, et al.


[Target] mouse, breast cancer

Cancers/Anti-oxidation

[Title]

ANTIOXIDANT AND ANTITUMOR EFFECTS OF MANDA


[Journal] Biochemical Archives Vol.14, 1998

[Author] Kim, et al.


[Target] mouse, liver, lung

[Title]

IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITIES OF EXTRACTS FROM A FERMENTED FOOD


[Journal] Journal of Food Biochemistry 27, 2003

[Author] Kim, et al.


[Target] test tube

Stress

[Title]

Manda Suppresses Emotional Stress-Induced Stomach Ulcers in Rats


[Journal] International Journal of Stress Management Vol.4 No.1, 1997

[Author] Kawai, et al.


[Target] rats, stomach ulcer

[Title]

Effect of a dietary fermented vegetable product on the heat shock response of Japanese flounder Paralichthys olivaceus


[Journal] Fisheris Science 75, 2009

[Author] Ashida, et al.


[Target] flounder, stress from outside the body

Alcohol consumption

[Title]

Inhibitory effect of MANDA on blood acetaldehyde concentration after alcohol administration (Japanese)


[Journal] Progress in Medicine Vol.18 No.7, 1998

[Author] Kawai, et al.


[Target] human, liver

Sexual function

[Title]

Experimental and Clinical Studies on the Effects of Manda Enzyme on Male Sexual Functions(Japanese)


[Journal] Journal of the Japanese Society of Impotence Research Vol.4 No.1/2, 1989

[Author] Koshido, et al.


[Target] human, sexual dysfunction

Infectious illness

[Title]

Immunostimulatory effects of fermented vegetable product on the non-specific immunity of Japanese flounder Paralichthys olivaceus


[Journal] Fisheris Science 71, 2005

[Author] Ashida, et al.


[Target] flounder, whole body

Menopause/Osteoporosis

[Title]

Effects of a Fermented Vegetable Product on Fat Deposition and Bone Metabolism in Ovariectomized Rats


[Journal] Journal of Nutritional Science and Vitaminology 50, 2004

[Author] Shimada, et al.


[Target] rats, weight gain, body fat

Anti-oxidation/Anti-aging

[Title]

MANDA SCAVENGES FREE RADICALS AND INHIBITS LIPID PEROXIDATION IN IRON-INDUCED EPILEPTIC FOCUS IN RATS


[Journal] Food and Free Radicals, 1997

[Author] Kawai, et al.


[Target] rats, cranial nerve

[Title]

Manda, a Fermented Natural Food, Suppresses Lipid Peroxidation in the Senescent Rat Brain


[Journal] Neurochemical Research Vol.23 No.4, 1998

[Author] Kawai, et al.


[Target] rats, brain

Formation of blood clot

[Title]

Isolation and Partial Characterization of a Polysaccharide with Antithrombin Activity against Blood Coagulation in Manda, a Fermented Natural Food


[Journal] Agricultural Chemistry and Biotechnology 43(4), 2000

[Author] Kim, et al.


[Target] test tube, thrombus

Clinical symptoms/Drug toxicity

[Title]

Experimental and Clinical Studies of Manda Enzyme on General Complaints of Hemodialysed Patients (Japanese)


[Journal] The Clinical Report Vol.23 No.10, 1989

[Author] Takara, et al.


[Target] human, whole body

Radiation damages

[Title]

“Shokubutsu hakko sanbutsu no X-sen shosha ni taisuru bougyo kouka – shocho no senka saisei ni ataeru eikyo”
(The defensive effects of a fermented vegetable product on X-ray exposure – effects on the regeneration of intestinal crypts)


[Journal] The Journal of Japan Mibyo System Association Vol.12 No.1, 2006

[Author] Ashida, et al.


[Target] mouse, small intestine

Growth/Feedstuff

[Title]

Effect of Diet Supplemented with a Fermented Vegetable Product on Lipid Peroxidation in Liver of Japanese Flounder, Paralichthys olivaceus


[Journal] SUISANZOSHOKU 50(1), 2002

[Author] Ashida, et al.


[Target] flounder, liver

[Title]

Effects of fermented plant product on growth performance, some blood variables, carcase characteristics, and intestinal histology in broilers


[Journal] British Poultry Science Vol.53 No.2, 2012

[Author] Lokaewmanee, et al.


[Target] chicken, intestine, body weight

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